There are 2 significant reasons for IVF failure, one of which is difficulties with the embryo. Not all embryos can create a live birth. Studies show that women 35 and under have about a 50% chance of success while those 42 and over have less than a 5% chance. Embryo abnormalities can cause this, such as embryos that do not mature successfully. In addition, some embryos don’t have enough chromosomes, which cannot be detected by a microscope. The more embryos, the better.
Understanding low ovarian follicle response
Poor or low ovarian follicle response occurs when the number of mature follicles obtained during an IVF cycle is lower than expected. Each follicle or fluid-filled sac in the ovary contains 1 immature egg. During the stimulation phase of IVF, hormonal injections help increase the natural output of mature eggs. The goal is to have at least 3 or more eggs develop during the cycle. When this goal is not met, the doctor can cancel the following steps. This could ultimately cause the current IVF cycle to fail.
Diagnosis and next steps
A woman can be diagnosed with low ovarian follicle response using an egg count or other ovarian reserve markers. Quantity is crucial in increasing the chances of success. In addition, a poor ovarian response can be caused by pituitary abnormalities, low egg reserve, or poor lifestyle habits. After a failed IVF, doctors recommend healthier decisions regardless of the prognosis. If all other methods fail and a woman’s egg reserve is fully depleted, an egg donor may be necessary.
There is hope
A failed IVF cycle can be distressing. However, this is an opportunity to learn, improve, and try again. Many factors determine the amount and health of ovarian follicles. However, taking charge of health by adopting a healthier lifestyle has benefits throughout every stage of the IVF journey. Even with donor eggs, maintaining a healthy lifestyle matters. Trying to conceive takes time and the right conditions and the IVF team can provide sound advice.