Is Your Endometrial Lining Ready For IVF?
Infertility is a common challenge at least 11% of women face. There are many possible causes but also potential treatment solutions. One such strategy is in vitro fertilization (IVF), a multi-step process that ends with implantation. This process places the created embryo into a woman’s uterine lining for pregnancy. Some women may have endometrial hyperplasia, which impacts natural fertility. This underlying condition must be addressed first to improve the chances of a successful IVF cycle.
Breaking down endometrial hyperplasia
Endometrial hyperplasia is an abnormal thickening of the endometrium or uterine lining. The endometrium is responsible for receiving the embryo and providing the nutrients during the initial stages of pregnancy. The endometrium goes through changes during each reproductive cycle, thickening in preparation for pregnancy. If pregnancy does not occur, the outer layers of the endometrium are shed during menstruation. With endometrial hyperplasia, there is an overgrowth of the tissue, leading to symptoms like irregular bleeding and hormone imbalances.
The link between hyperplasia and fertility
With endometrial hyperplasia, the thickened endometrial lining may lead to difficulties with egg implantation, reducing the chances of pregnancy. The condition is often caused by a hormone imbalance, such as an excess of estrogen in relation to progesterone. Along with a thickened uterine lining, the condition disrupts the menstrual cycle and ovulation. The condition can lead to repeated miscarriages or failed implantation, leading to infertility. In rare cases, atypical endometrial hyperplasia may progress to endometrial cancer if left untreated. With the right diagnosis and treatment, the condition can be addressed, increasing fertility.
Diagnosis and treatment for IVF success
Women undergoing IVF may encounter challenges with endometrial hyperplasia. Early diagnosis and treatment can improve fertility and the success rate of IVF. A transvaginal ultrasound can help identify the thickness of the uterine lining. A doctor may also suggest an endometrial biopsy. A small tissue sample is removed in a quick outpatient procedure. The sample is then placed under a microscope to determine the type of endometrial hyperplasia present. Treatment will depend on the type of hyperplasia and how much influence the condition has on IVF cycles.
Optimizing treatment for IVF success
Treatment can improve the uterine lining and, therefore, the success of IVF. Hormone therapy, such as birth control pills or progestin medication, regulates hormones causing the condition. Over time, the uterine lining improves, and there is an increased chance of pregnancy. Lifestyle changes such as maintaining weight, regular exercise, and limiting alcohol consumption also contribute. These changes can support IVF cycles and may increase success rates. In some cases, a doctor may recommend a surgical procedure to remove part of the uterine lining. This is often a last resort if hormone treatment fails or if the patient has atypical hyperplasia.
A healthier uterine lining matters
The endometrium plays a vital role in pregnancy. A delicate balance is necessary for a successful implantation. If the lining is abnormally thick, there will be challenges with fertility and with IVF cycles. If endometrial hyperplasia is left untreated, there will be challenges with IVF. Early testing and diagnosis are recommended during any IVF cycle. Improving the health of the uterine lining can improve fertility. With hormone therapy and other strategies, pregnancy is on the horizon.
