Tapping Into Platelet Power With PRP

Every year, in vitro fertilization (IVF) unlocks the possibility of parenthood for thousands of couples. By creating viable embryos, IVF bypasses the challenges caused by infertility. While effective, IVF still has a minimum 50% success rate, often requiring multiple cycles. Doctors and patients are always looking for ways to improve IVF outcomes, as any advantage counts. Recently, doctors have seen promise in platelet-rich plasma (PRP) therapy as a form of ovarian rejuvenation. PRP is popular in other health and wellness spaces. There may be some evidence that this form of regenerative medicine may be advantageous during IVF treatment.

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Understanding PRP

Platelet-rich plasma is a process that separates platelets from a patient’s blood. First, a doctor or medical professional draws a blood sample from a patient. The sample is spun at high speed in a centrifuge. This step separates the red blood cells from the plasma. The plasma contains platelets, which have fantastic healing and regenerative properties. The platelet solution, along with a bit of plasma, is then injected into another part of the body. For instance, PRP can help manage pain, heal injuries like tendinitis, or support tendon repair. PRP can also help trigger hair growth or collagen production. Doctors and scientists are constantly finding new applications for PRP as a form of natural healing without the use of medication.

How PRP infiltrated the IVF lab

Doctors have begun experimenting with PRP in the reproductive health space. The rationale is that the entire body is at risk of oxidative stress and cellular damage, even if these changes do not show on fertility tests. Therefore, introducing healing factors like PRP can lower inflammation and may even restore organ tissue by activating more stem cells. Doctors first used PRP injections in the uterus to help with the endometrial lining. Now, PRP injections are used for ovarian rejuvenation.

Producing egg-cellent results

PRP can assist with ovarian rejuvenation. The goal is to support healthy ovaries so high-quality follicles can be produced for IVF. The medical team will prepare the PRP and inject the solution directly into the ovaries using an X-ray technique called fluoroscopy. This regenerative medication should reduce inflammation and may even restore parts of the ovaries. PRP therapy is performed periodically, beginning several weeks or months before the egg harvesting stage. The doctor may also attempt PRP during the harvesting process, which should not disrupt hormone medication.

Is there evidence that PRP helps IVF?

PRP is ideal for women with failed IVF cycles, repeated miscarriages, or for those with a declining ovarian reserve. If there are concerns with egg quality, this can provide an additional boost. A study of 469 women with varying degrees of ovarian failure saw improved function and tissue growth. Some women with a diminished ovarian reserve also develop more high-quality follicles while using PRP. PRP for ovarian rejuvenation is in the infancy stages, but initial results look promising. As more research surfaces, more fertility clinics will consider PRP therapy.

A hidden key to improved IVF outcomes

The IVF objective is to achieve a healthy pregnancy and, ultimately, a live birth. Anything that can improve ovarian health and boost IVF outcomes is welcomed. PRP can provide the ovaries with some regenerative help thanks to the growth factors contained in platelets. Consistent use may see improvements. Success rates may depend on age, health, and receptivity. Over time, more fertility clinics will welcome, encourage, and provide PRP as part of the IVF experience.

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